Inherited Cancer, Haematologic and Dermatological Diseases Programme

Inherited Cancer and Related Syndromes Programme: this consists of 9 research groups from different fields, from clinical and molecular genetics to regenerative medicine, advanced/innovative therapies, molecular biology and cell biology.

Rare diseases studied

  • Fanconi anaemia and disorders connected with genetic instability.
  • Inherited cancer and paediatric tumours.
  • Rare dermatological diseases and skin bioengineering
  • Other rare anaemias and coagulopathies

Objective

To study the physiopathological mechanisms and genetic bases of inherited cancer as well as other related syndromes, in which genetic instability is a fundamental component involved in the appearance or progress of the disease.

    In addition, this Research Programme includes groups related to genetic-based dermatological and haematologic pathologies.

    The specific objectives of this programme focus on chromosome research, specifically into Fanconi Anaemia, research on rare tumours, particularly endocrinal tumours and research on advanced therapies (in cooperation with other PdI). Some of its most outstanding achievements are the international clinical tests for gene therapy of Fanconi anaemia or the development of tissues in culture for autologous transplant after gene correction for epidermolysis bullosa.

    Research groups of the PdI

    Main ResearcherInstitutionProvinceDetails
    Robledo Batanero, Mercedes Fundación Centro Nacional de Investigaciones Oncológicas Madrid
    Botella Cubells, Luisa María Agencia Estatal Consejo Superior de Investigaciones Científicas Madrid
    Bueren, Juan Antonio Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT) Madrid
    Caballero Molina, María Teresa Servicio Madrileño de Salud Madrid
    del Río Nechaevsky, Marcela Universidad Carlos III Madrid
    Fernández Piqueras, José Universidad Autónoma de Madrid Madrid
    Perona Abellón, Rosario Agencia Estatal Consejo Superior de Investigaciones Científicas Madrid
    Surrallés, Jordi Universidad Autónoma de Barcelona Barcelona
    Vicente Garcia, Vicente Fundación para la Formación e Investigación Sanitarias de la Región de Murcia (FFIS) Murcia
    Scientific Programme Manager Dr. Juan Luque