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• Osteogenic regeneration . This research line was introduced in our department recently as a result of collabo- ration with the group COFIBIC, coordinating group, of an autonomic project BIOINTEL, that has continued with another project, “BITI” award in 2010 until 2014 . We have worked on the regeneration of bone defects using tissue engineering techniques and on the biocompatibility of bone substitutes in different experimental models .
Most relevant scientific articles
• PasCual g., Pérez-kohler B., roDríguez M., sotoMayor s., Bellón J.M. Postimplantation host tissue response and biodegradation of biologic versus polymer meshes implanted in an intraperitoneal position . Surgical Endosco- py and Other Interventional Techniques . 2014;28(2):559-569 .
• garCía-Moreno F., sotoMayor s., Pérez-lóPez P., Pérez-kohler B., Bayon y., PasCual g. et al . Intraperitoneal be- haviour of a new composite mesh (ParietexTM Composite Ventral Patch) designed for umbilical or epigastric hernia repair . Surgical Endoscopy . 2014 .
• siMon-allue r., Pérez-lóPez P., sotoMayor s., Pena e., PasCual g., Bellón J.M. et al . Short- and long-term biome- chanical and morphological study of new suture types in abdominal wall closure . Journal of the Mechanical Behavior of Biomedical Materials . 2014;37:1-11 .
• MalDonaDo a.a., CristóBal l., Martín-lóPez J., Mallen M., garCía-honDuVilla n., BuJÁn J. A novel model of human skin pressure ulcers in mice . PLoS ONE . 2014;9(10) .
• Pérez-riCo C., PasCual g., sotoMayor s., asunsolo a., CiFuentes a., garCía-honDuVilla n. et al . Elastin development- associated extracellular matrix constituents of subepithelial connective tissue in human pterygium . Investigati- ve Ophthalmology and Visual Science . 2014;55(10):6309-6318 .
Highlights
Institution: Universidad de Alcalá Contact: Facultad de Medicina . Campus Univ . Ctra . Madrid-Barcelona, km . 33,6 . 28871 Alcalá de Henares, Madrid · Tel .: (+34) 91 885 45 40 · E-mail: juanm .bellon@uah .es https://portal .uah .es/portal/page/portal/grupos_de_investigacion/57/Presentacion
The third year of the coordinated national project DPI2011-27939-C02-02, “Diseño de prótesis biomiméticas con adaptación a las propiedades del tejido receptor”, included in our main line of research in abdominal wall hernia repair, as part of the CIBER intramural project ABDOMESH/BIOMIMESH, has been carried out successfully during 2014 . One contract of transfer (Art . 83), related to prosthetic infection, with the company Covidien, has finished and another project signed with LifeCell, on the behavior of different biological collagen prostheses, has been developed . This research line has had a significant scientific productivity during 2014, with a total of ten publications (three of them included in 1st JCR quartile (Q) and 5 in the 2nd Q) . In connection with this research line, several communications have been presented to the 16th Annual Hernia Repair and 36th International Congress of the European Hernia Society, held in Las Vegas and Edinburgh and to the III International Conference on Antimicrobial Research held in Madrid .
Regarding our research line in repair of skin defects, a paper in PLoS One (1oQ) on a new pressure ulcer model in mice was published . During this year a major contract of transfer with the company Novartis, in the field of drug healing, has been developed . Respect to the research line of vascular repair, during 2014 the first year of the National Research Project on venous insufficiency, funded by the Instituto de Salud Carlos III (PI13 / 01513) was carried out successfully . Several communications have been presented to the 30th Meeting on Vascular Research LIAC held in Valladolid .
In November 2014 a national patent application (P201431678) entitled “Methods of cell removal” has been presented in collaboration with the National Institute for Research and Agricultural and Food Technology (INIA) . Additionally, an article in the IOVS journal (1oQ) has been published and a communication has been presented to the 8th European Elastin Meeting, related to ocular pathology .
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