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RESEARCH GROUPS
Translational Research Group
in Biomaterials and Tissue Engineering
Programme: Biomaterials and Advanced Therapies
Lead Researcher: Bellón Caneiro, Juan Manuel Group Members
STAFF MEMBERS: González Chamorro, Diana | Martínez-Alcocer Fuerte, Soraya | Pascual González, Ma Gemma
ASSOCIATED MEMBERS: Buján Varela, María Julia | García Honduvilla, Natalio CONTRIBUTORS: Pérez Köhler, Bárbara | Trejo Iriarte, Cynthia Georgina
Main lines of research
• Biomaterials for the repair of abdominal wall defects . This research has the purpose of repairing damaged and/or missing tissues mainly located in the abdominal wall . Several types of biomaterials for clinical use have been used in this line as supports, new designs and modifications thereof being developed . Different collagen bioprostheses as well as composites meshes and prosthetic materials with polymeric coatings that can reduce inflammation, accelerate healing process or prevent contamination are currently being assayed .
• Repair of skin defects . One of the alternatives for the repair of skin defects, especially in patients with compro- mised healing (diabetics, torpid vascular ulcers and pressure ulcers) can be improved through tissue enginee- ring strategies . Essentially work is being conducted with two experimental models: muscle-derived stem cells for repairing excisional skin defects with encouraging results, and the design of polymers for the controlled release of healing modulating drugs .
• Vascular repair . Work has been conducted within this line in healing/ restenosis, with special interest in the mo- dulation thereof, concluding that intimal hyperplasia is a result of the vascular wall healing process, which has the objective of maintaining homeostasis of the damaged vessel . The problem of arterial substitution by means of biomaterials for clinical use and cryopreserved vessels has also been approached . Finally, tissue engineering techniques are used for the purpose of improving the viability of prosthetic materials through the creation of a cell coating and the incorporation of bioactive substances .
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CIBER-BBN » Annual report 2014