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COMPOUND MATERIAL BY POLYMER AND METALLIC PARTICLES FOR BIOMEDICAL APPLICATIONS
Spanish Patent ES 2372341 B1
The present invention refers to a material with a polymeric matrix and metallic particles . It provides a biocompatible and bio-degradable material for the manufacturing of useful devices for medical applications such as material for bone-synthesis and tissue engineering for the regeneration of bone tissue .
A first aspect of the present invention refers to a material comprising a biodegradable polymer and metallic particles . A second aspect of the present invention refers to a procedure for obtaining the biomaterial . A third aspect of the present invention refers to the use of this biomaterial for the manufacture of an implant or biomedical device for the repair and regeneration of bone tissue .
DEVICE AND METHOD FOR INTAKE MONITORING
Spanish Patent ES 2353711 B2
The invention consists in a method of transparent monitoring of the intake, a monitoring device and a method to associate overall weight variations to individual containers . Transparent monitoring is that where the guest has meals in the most possible similar way to a situation in the absence of monitoring . This is a historical challenge for intake monitoring .
The present invention proposes a method and a device for the transparent intake monitoring . A solution for the transparent monitoring of the intake is achieved because the method can, at any moment, automatically associate the weight variation, detected by a sole measurement in a containers bearing surface, to the container where it was originated .
The invention also comprises a monitoring device specifically designed for this kind of measurements and association .
LIPOPHILIC DERIVATIVES OF NUCLEIC ACIDS
Spanish Patent ES2368300B1
In this invention, new siRNA derivatives are described, which facilitate siRNA cellular administration, and are more stable to nucleases, what makes them more effective for the inhibition of gene expression . These siRNA duplex can be transfected into human cells, efficiently entering the cells where they triggers the siRNA mechanism, in a similar way to the unmodified ones, including the specific inhibition of the gen with the complementary sequence to the siRNA .
Synthesis procedures are described as well . Moreover, another aspect of the invention is the pharmaceutical compositions containing, at least, an excipient or pharmaceutical vehicle . An excipient comprises any inert material used in the preparation of a form for dosage . A particular kind of excipients is the transfection agents, which improves the vector properties .
The administration of these compounds can be oral, parenteral, intravenous, intramuscular subcutaneous, intra-duodenal, etc .
MAGNETIC-LUMINESCENT PARTICLES FOR BIO-MEDICALS APPLICATIONS
Spanish Patent ES 2367959 B1
The authors have developed a system of magnetic-luminescent particles, with a size inferior to three microns, and the procedure for its preparation . They can present a luminescence of high efficacy in the near infrared spectrum and in the whole visible one, from 400 to 1500 nm (blue to near IR) . The luminescence can last until one week after the synthesis . The particle surface can be modified by linking
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