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RESEARCH GROUPS
Applied Molecular Chemistry Group
of the IDM
Programme: Nanomedicine / Biomaterials and Advanced Therapies
Lead Researcher: Martínez Máñez, Ramón Group Members
STAFF MEMBERS: Aznar Gimeno, Elena | García Fernández, Alba
ASSOCIATED MEMBERS: Benito Beorlegui, Ángel Francisco | Coll Merino, María del Carmen | Lizondo Sabater, Josefina | Marcos Martínez, Ma Dolores | Murguia Ibáñez, José Ramón | Pardo Vicente, Teresa | Sancenón Galarza, Félix | Villaescusa Alonso, Luis Ángel | Vivancos Bonos, José Luis
CONTRIBUTORS: Barba Bon, Andrea | Bataller Prats, Román | De la Torre Paredes, Cristina | El Sayed Shihata Nasr, Sameh | Giménez Morales, Cristina | Mas Font, Nuria | Moragues Pons, María Esperanza | Oroval Cucarella, Ma del Mar | Pascual i Vidal, Lluís | Sanfeliú Cano, Cristina | Santos Figueroa, Luis Enrique
Main lines of research
• Development of nanometric devices with ‘molecular gates” for controlled release. Our objec- tive is to develop nano-systems containing “molecular gates” for releasing a certain payload at will . For that purpose, nanometric mesoporous solids are used as support . Such gated mesoporous silica nanoparticles are able to retain a cargo inside the pore system and deliver it upon the application of a target chemical (redox molecules, selected anions, pH changes, etc .), physical (such as temperature, magnetic fields or light) or biochemical (such as enzymes, antigens, DNA) stimuli .
• Molecular probes . We have experience in developing molecular chemical probes in which the recog- nition process is coupled to signaling . This applies to the design of probes for the in vitro or in vivo chromo-fluorogenic detection of molecules of interest .
• Transverse capacities . Organic and inorganic synthesis Preparation/functionalization of mesoporous materials Preparation/functionalization of inorganic nanoparticles (gold, silver, oxides, silica, etc)
102 CIBER-BBN » Annual report 2014