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• Processing and characterization of biomedical signals in respiratory pathologies . The ambulatory diagnosis of patients suffering from sleep diseases is a very relevant health challenge . Solving this challenge from easy to record biomedical signals (ECG, PPG) will represent a huge advance . We target the characterization of these signal changes following respiratory patterns changes, as deep of respiration, frequency, the obstructive or central apnea occurrence and their relation to cardiovascular disorders .
Most relevant scientific articles
• DeMiDoVa M.M., Martin-yeBra a., Van Der Pals J., koul s., erlinge D., laguna P. et al . Transient and rapid QRS- widening associated with a J-wave pattern predicts impending ventricular fibrillation in experimental myocar- dial infarction . Heart Rhythm . 2014;11(7):1195-1201 .
• sÁnChez C, Bueno-oroVio a, WettWer e, loose s, siMon J, raVens u et al . Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation .PloS one . 2014;9 (8):e105897 .
• MeiJs l.P.B., galeotti l., Pueyo e.P., roMero D., Jennings r.B., ringBorn M. et al . An electrocardiographic sign of ischemic preconditioning . American Journal of Physiology - Heart and Circulatory Physiology . 2014;307(1) . • lÁzaro J., alCaine a., roMero D., gil e., laguna P., Pueyo e. et al . Electrocardiogram Derived Respiratory Rate
from QRS Slopes and R-Wave Angle . Annals of Biomedical Engineering . 2014;42 (10):2072-2083 . • alCaine a., soto-iglesias D., CalVo M., guiu e., anDreu D., FernÁnDez-arMenta J. et al . A wavelet-based electro- gram onset delineator for automatic ventricular activation mapping . IEEE Transactions on Biomedical Engi-
neering . 2014;61(12):2830-2839 .
Highlights
Institution: Universidad de Zaragoza Contact: Universidad de Zaragoza . Calle Pedro Cerbuna, 12, 50018 Zaragoza · Tel .: +34 876 555 651 E-mail: laguna@unizar .es · http://diec .unizar .es/~laguna/personal/publicaciones/publicaciones .htm
• Award of a ERC “Starting grant” from H2020 program led by Esther Pueyo entitled: MODELAGE: Modeling and characterization of cardiac aging .
• Funding of a project from Spanish national research plan, led by Juan Pablo Martínez: TEC2013-42140-R: procesado de señales guiado por la fisiologia para la estratificacion del riesgo cardiovascular y guiado de la terapia: herramientas para mejorar la toma de decisiones
• Funding of a project from Spanish national research plan, led by Esther Pueyo: TIN2013-41998-R: el sistema nervioso autonomo como modulador de la funcion cardiaca: investigación integral mediante procesado de señal y modelado computacional
• Funding of a project from the program: proyectos colaborativos multidisciplinares de transferencia tecnológi- ca en patologías respiratorias CIBER-BBN-CIBERES-SEPAR: PVI-ANS-NCOG: Effects of an early neurocognitive intervention on patient-ventilator interaction and stress in critically ill patients receiving mechanical ventilation
• Assumption of the presidency of the Board of Directors from “Computing in Cardiology” by the PI of the group Pablo Laguna, for the period 2014-2017 .
Additionally the group has published a total of 21 papers and 24 conference proceedings, From those it is worthy to highlight three reviews on signal processing applied in Physiology:
• A. Bueno-Orovio, C. Sánchez, E. Pueyo, B. Rodriguez (2014). Na/K pump regulation of cardiac repolariza- tion: insights from a systems biology approach . Eur J Physiol . INVITED REVIEW . 466:183–193 doi: 10 .1007/ s00424-013-1293-1
• A Roebuck, V Monasterio, E Gederi, M Osipov, J Behar, A Malhotra, T Penzel, G D Clifford (2014), A review of signals used in sleep analysis . Physiological Measurement . vol . 35 R1–R57 doi:10 .1088/0967-3334/35/1/R1 . • P. Laguna, L. Sörnmo (2014). The STAFF III ECG Database and its Significance for Methodological Development
and Evaluation, Journal of Electrocardiology, n .47; pp . 408–417 doi:10 .1016/j .jelectrocard .2014 .04 .018 .
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