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Most relevant scientific articles
• góngora-Benitez M., tulla-PuChe J., alBeriCio F. Multifaceted roles of disulfide bonds . peptides as therapeutics . Chemical Reviews . 2014;114(2):901-926 .
• PuliDo D., alBeriCio F., royo M. Controlling multivalency and multimodality: Up to pentamodal dendritic plat- forms based on diethylenetriaminepentaacetic acid cores . Organic Letters . 2014;16(5):1318-1321 .
• Fransen P., PuliDo D., seVrin C., granDFils C., alBeriCio F., royo M. High control, fast growth OEG-based dendron synthesis via a sequential two-step process of copper-free diazo transfer and click chemistry . Macromolecules . 2014;47(8):2585-2591 .
• Just-Baringo X., alBeriCio F., ÁlVarez M. Thiopeptide engineering: A multidisciplinary effort towards future drugs . Angewandte Chemie - International Edition . 2014;53(26):6602-6616 .
• De la torre C., CasanoVa i., aCosta g., Coll C., Moreno M.J., alBeriCio F. et al . Gated mesoporous silica nano- particles using a double-role circular peptide for the controlled and target-preferential release of doxorubicin in CXCR4-expresing lymphoma cells . Advanced Functional Materials . 2014 .
Highlights
Institution: Fundación Privada Instituto de Recerca Biomédica (IRB-Barcelona) Contact: Fund . Priv . Instituto de Recerca Biomedica (IRB) . C/ Josep Samitier, 1-5 . 08028 Barcelona . E-mail: albericio@irbbarcelona .org http://www .irbbarcelona .org/index .php/en/research/programmes/chemistry- and-molecular-pharmacology/ combinatorial-chemistry-for-the-discovery-of- new-compounds/people/fernando-albericio
In 2014, the peptide and nanoparticles group has published a total of 60 publications in international journals, some of them are high impact factor publication (Angewandte Chemie, Chemical Reviews, Advanced Functional Materials, Macromolecules . . .) Some of these publications described the synthesis of diverse marine-derived drugs with potent antitumoral properties . Others describe the use of a new family of oligoethylene glycol based dendrimers on diverse applications . In addition, Fernando Albericio Palomera, IP of the group, was honored with the “Premio a la Excelencia Investigadora 2014” from RSEQ and the “Premio a la Excelencia en Investigación” GEPRONAT 2013, in recognition of his career research .
During this year, financial resources have been provided by various national and international agencies that include four national grants and a private foundation project . The group has three collaborative projects with pharmaceutical and biotech companies founded by competitive grants (NANOCARDIOCOCO, HUMANFARMA and MARINMAB, INNPACTO-MINECO) . The group also applied and granted other two national collaborative project (RETOS-COLABORACION RTC-2014-2557-1 and TERARMET) that were initiated in 2014 . Furthermore, in 2014 has began the PENTRI project focused on the development of personalized nanomedicine for breast cancer founded by the La Marató de TV3 2012 call . In addition, the group was granted with Technology Transfer Project from the CIBERBBN,(LIPOCELL), focused on the development of a protein delivery system for Fabry disease . In the frame of the LIPOCELL project, a patent from our group, in collaboration with other CIBER BBN groups, was licensed to Biopraxis .
Collaborations have been established and continued at the national environment (IBEC, IRB, Hospital Vall d’Hebró, CIB-CSIC, Universitat Autònoma de Barcelona, Universitat de Barcelona, Universidad de Santiago de Compostela) and international levels (Chile, Argentina, Brasil, Portugal, Netherlands, Belgium, South Africa and Denmark) ,as well as, several collaborative projects being carried out with companies from the pharmaceutical and biotechnology sectors .
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