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• Devices . The goal at this level is to develop microsensor devices, multi-micro sensors, sensing arrays or sensor platforms for measuring physical, chemical and biological parameters and components such as oxygen, impedance, pH, different type of anions and cations, temperature, or proteins, for example, using an integrated unique device . The ultimate objective is to enable easy multiple monitoring in applications requiring multiparametric control .
• Systems/Applications . The developed technologies and devices will constitute useful tools to be used both on the experimental bench as well as in medical and clinical applications .
GBIO group has developed during the last few years an outstanding expertise in the design and fabrication of Micro-Nano-Bio devices based either on silicon or biocompatible polymers . Biological signals obtained with these devices are usually subjected to post-acquisition conditioning and processing with the help of totally integrated systems .
Most relevant scientific articles
• Ventayol M., Vinas J.l., sola a., Jung M., Brune B., Pi F . et al . MiRNA let-7e targeting MMP9 is involved in adiposederived stem cell differentiation toward epithelia . Cell Death and Disease . 2014;5(2) .
• Del CaMPo F.J., aBaD l., illa X., Prats-alFonso e., Borrise X., Cirera J.M . et al . Determination of heteroge- neous electron transfer rate constants at interdigitated nanoband electrodes fabricated by an optical mix-and-match process . Sensors and Actuators, B: Chemical . 2014;194:86-95 .
• silVe a., guiMera Brunet a., al-sakere B., iVorra a., Mir l.M . Comparison of the effects of the repetition rate between microsecond and nanosecond pulses: Electropermeabilization-induced electro-desensi- tization? . Biochimica et Biophysica Acta - General Subjects . 2014;1840(7):2139-2151 .
• guiMera X., Moya a., DoraDo a.D., Villa r., gaBriel D., gaBriel g . et al . Biofilm dynamics characterization using a novel DO-MEA sensor: mass transport and biokinetics . Applied Microbiology and Biotechno- logy . 2014;99(1):55-66 .
• esteVe V., Berganzo J., Monge r., Martinez-BisBal M.C., Villa r., CelDa B . et al . Development of a three- dimensional cell culture system based on microfluidics for nuclear magnetic resonance and optical monitoring . Biomicrofluidics . 2014;8(6) .
Institution: Universidad Autónoma de Barcelona Contact: Centro Nacional de Microelectrónica . Campus Univ . Autónoma de Barcelona . 08193 Bellaterra-Cerdanyola del Vallés · Tel .: (+34) 93 594 77 00 ext . 2459 · E-mail: jordi .aguilo@uab .es
www .ciber-bbn .es 61