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RESEARCH GROUPS
Small Biosystems Lab
Programme: Nanomedicine
Lead Researcher: Ritort Farran, Félix Group Members
STAFF MEMBERS: Pastor del Campo, Isabel ASSOCIATED MEMBERS: Huguet, Josep María | Palassini, Matteo
CONTRIBUTORS: Alemany, Anna | Bongini, Lorenzo | Camuñas Soler, Joan | Mañosas Castejón, María | Rey Serra, Blanca | Ribezzi Crivellari, Marco .
Main lines of research
• The research group led by Dr . Ritort investigates the energetic of biological processes at the molecular level in the broadest sense, from the fundamental understanding of irreversible phenomena at the microscopic scale to the most advanced applications that can characterize and measure molecular interactions with a resolution of tenths of kilocalories per mole (kcal/mol) . All this is done through a multidisciplinary approach combining single molecule experiments and biochemical measures of phe- nomenological theories used in the field of biophysics, as well as fundamental principles of statistical physics applied to physicochemical systems out of equilibrium .
• Characterized the broad perspective our research gives a wide range of applications ranging from the study of the binding of a peptide to protein, aggregation kinetics of complexes formed by drugs that bind to nucleic acids and the study of interactions antigen-antibody .
• Our group is internationally recognized for having made fundamental advances in the understanding and characterization of the energetic of folding and assembly of nucleic acids, characterization of molecular motors that regulate DNA replication and fundamental theories describing the behavior of disordered systems out of equilibrium . Over the coming years we will continue working on these lines of research that have proved so profitable .
120 CIBER-BBN » Annual report 2014