Page 119 - MEMOCiberesp014-ENG

Highlights
The CMR[B] is a research centre focused on the investigation of the mechanisms that regulate cell di- fferentiation and patterning during development and regeneration . In the same manner, the general activity of the center is orientated towards the research in regenerative medicine, with special emphasis in the generation of patient-derived induced pluripotent stem cells (iPSCs) for disease modelling . Our goal is to define efficient protocols for the differentiation of mesenchymal stem cells (MSCs) from hu- man tissues (adipose and bone marrow tissues) and iPSCs towards bone, cartilage, retinal pigmented epithelial cells, hematopoietic cells and cardiac muscle cells . Our newly defined protocols include the use of soluble factors, chemically defined media, biomatrices and tissue-specific genes .
In order to accomplish our aims we have been working in collaboration with Dr . Ivon Cusco from the CIBERER-UPF, Dr . Juan Bueren from CIBERER-CIEMAT, among other collaborating studies .
Besides, we have continued collaborating with Dr . Elena Martínez (IBEC; CIBER-BBN) . As result of this research, we presented a poster at the 8th CIBER-BBN Annual Conference (10-11/11/2014, Girona):
Authors: E . Garreta, A . G . Castaño, E . Martínez, A . Raya
Title: Derivation of retinal neurons from human induced pluripotent stem cells on top of hydrogel substrates with different topographies
Dr . Bedford presented a research project to the ISCIII, AES 2014 call, which was granted:
PI14/02184 Desarrollo de una plataforma de reprogramación de alto rendimiento basada en extractos de ovocito empaquetados en liposomas
Furthermore, our group, as coordinator team, presented a proposal to the ISCIII, AES 2014 call for CIBER’s Integrated projects of Excellence and this proposal was selected for funding:
PIE14/0061 Molecular links between diabetes and neurodegenerative disorders Coordinator PI: Ángel Raya Total funding amount: 660 .000€ Project duration: 01/01/2015 - 31/12/2017
Twelve groups from different CIBER (CIBERER, CIBERNED, CIBERDEM, CIBERBBN) are involved in this project .
Institution: Centro de Medicina Regenerativa de Barcelona Contact: Centro de Medicina Regenerativa de Barcelona · Dr . Aiguader 88, 7a planta . 08003 Barcelona E-mail: director@cmrb .eu · Website: www .cmrb .eu
www .ciber-bbn .es 119