Page 98 - MemoriaBBN-Eng

RESEARCH GROUPS

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PROGRAMME:
Bioengineering Endocrinology and Diabetes Research Group

and Medical Imaging

Lead Researcher
Group Members
Leiva Hidalgo, Alberto
STAFF MEMBERS
Bell Ramrez, Olga Lidia

íMato Matute, Ma Eugenia
Contact:
ASSOCIATED MEMBERS
Grupo de Investigación en Endocrinología y Diabetes. ó
Inst. de Investigacin del Hsp. de la Sta. Cruz y San Pablo. Chico Ballestero, Ana Isabel
C/. San Quintn, 89 · Laboratorios, bl. B, pl. 2. Barcelona. Corcoy Pla, Rosa

E.mail: [email protected]
CONTRIBUTORS
Cubero Marcos, Jos Mara
Main lines of research
Gonzlez Blanco, Cintia

THYROID CANCER
•
Markers of prognostic prediction.
- Implication of 21 genes in CDT. Development of data base, and a private collec-

tion of serum and tissue bank of epithelial thyroid cancer (more of 200 cases).
We found he relationship between the expression of ABCG2/BRCP transporter

gen and the aggressiveness of the TPC-1human cell-line of thyroid cancer. We
have identified differential hyper-and under-expression of genes in PTC and

FTC. 120 proteins have been identified by proteomic analysis.
• In vitro e in vivo evaluation of a an original thyroid chemotherapy.

- PGLA nanoparticles, loaded with an inhibitor of tyrosinkinase, recognize the

neoplastic cells by a monoclonal antibody against EGFR.
DIABETES MELLITUS, METABOLIC SYNDROME, OBESITY, CARDIOMETABOLIC RISK 13
20
• Autoimmune Diabetes Mellitus.
T
R
- EU Research Consortium that has characterized the genetics, the immunology, PO
the metabolic and the clinical phenotype of LADA in 11 european countries
E
L R
• Telemedicine and Intelligent Systems for the Therapeutical Optimization of Dia- A
NU
betes Mellitus.
N
- PREDIRCAM Project. Original technological platform of CIBER-BBN, previously A
/
validated; at present, a multicentric clinical trial is being developed in 3 Spanish BN
University Hospitals. (Coordination, EDUAB-HSP)
B
R-
- CONCEPTT: Continuous Glucose Monitoring (CGM) in Women with Type 1 Dia- BE
CI
betes in Pregnancy Trial. First worldwide clinical trial to demonstrate the benefits
98
of CGMS in diabetic pregnancy. EDUAB-HSP is a Member of the Steering Com-

mittee too (countries involved: Canada, Israel, Italy, Spain USA).