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• v-r v, P-o mA, G-m ml, B Jm, G-m-
AdilloodríGuezAChAlivenzAónzAlezArtínruqueAllArdooMost relevant
reno Am. Adsorption behavior of human plasma fibronectin on hydrophobic and hy-
scientific drophilic Ti6Al4V substrata and its influence on bacterial adhesion and detachment.J

articles
Biomed Mater Res A. 2013;101A(5):1397-1404.

• GAlán-lAdero mA, BlAnCo-BlAnCo mt, hurtAdo C, Pérez-GirAldo C, BlAnCo mt, Gómez-

GArCíA AC. Determination of biofilm production by Candida tropicalis isolated from
hospitalized patients and its relation to cellular surface hydrophobicity, plastic adhe-

rence and filamentation ability.Yeast. 2013 Sep;30(9):331-9.

• PAChA-olivenzA mA, GAllArdo-moreno Am, vAdillo-rodríGuez v, González-mArtín ml, Pérez-
G C, G JC. Electrochemical analysis of the UV treated bactericidal Ti6Al4V
irAldoAlván
surfaces.Mater Sci Eng C Mater Biol Appl. 2013 Apr 1;33(3):1789-94.

• rodríGuez-CAno A, CintAs P, Fernández-CAlderón mC, PAChA-olivenzA má, CresPo l, sAldAñA
l .. Controlled silanization-amination reactions on the Ti6Al4V surface for bio-
et Al
medical applications.Colloids Surf B Biointerfaces. 2013 Jun 1;106:248-57.

• sAAdeddin A, rodriGo-nAvArro A, monedero v, riCo P, morAtAl d, González-mArtín ml et
ó
Al.. Functional living biointerphases.Adv Healthc Mater. 2013 Sep;2(9):1213-8.

The research activity during 2013 has focused on two different projects asso-
Highlights
ciated to private entities. In one case, the collaboration is carried out within the
framework of a project INNPACTO, with the aim of characterizing different me-

tal coatings that could potentially be used in prosthetic implants. This research
makes use of the equipment provided by the “Plataforma de Calorimetría y Carac- ó

terizacin Superficial”. In the other case, being fully financed by the company, the

project is based on evaluating the response of a metal to possible infections after
subjecting its surface to different treatments generated by the own company. In

this line, a new contact with a third private entity was also established, the last

details of a formal collaboration now being discussed.

Moreover, we have begun to work together with the “Servicio de Cirugía Oral y
Maxilofacial del Hospital Universitario Infanta Cristina de Badajoz”. Several stu-

dies have begun within this collaboration, one of them published already in a
scientific journal, and also the initiation of a PhD dissertation on the characteriza-

tion of explanted devices.

The research work associated to the project financed within the “Subprograma de

Proyectos de Investigacin Fundamental no Orientada” (Call 2012) has also been
initiated. This project is based on a new polymer-metal composite on which the

initial adhesion of different bacterial strains and the subsequent development of

biofilms are being evaluated and related to its surface characteristics.

The influence of surface topography on bacterial adhesion has also been studied
using spatially organized micro nano-topographic surface patterns generated on 13
20
a polymeric material. In addition, studies have been carried out on the precursor T
layer of proteins on some metal surfaces. Also, the work related to the charac- OR
P
terization of yeast biofilms associated to hospitalized patients continued. Finally, RE
L
the research on the bactericide behavior of treated Ti6Al4V surface was advanced.
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