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• Design of bioreactors for biomimetic stimulation of cell cultures with special focus on the application of con- trolled strains and flow .
• Development of microactuators, microfluidic networks, etc . for the study of cell biology under in vitro biomi- metic enviroments .
• Design, fabrication and development of novel in vitro diagnostic systems based on microfluidic systems . • Microtechnology for life science applications .
Most relevant scientific articles
• esteVe V., Berganzo J., Monge r., Martínez-BisBal M.C., Villa r., CelDa B. et al . Development of a three-dimen- sional cell culture system based on microfluidics for nuclear magnetic resonance and optical monitoring . Biomicrofluidics . 2014;8(6) .
• MousaVi s.J., DoBlaré M., DoWeiDar M.h. Computational modelling of multi-cell migration in a multi-signalling substrate . Physical Biology . 2014;11(2) .
• Cilla M., Pena e., Martínez M.a. Mathematical modelling of atheroma plaque formation and development in coronary arteries . Journal of the Royal Society Interface . 2014;11(90) .
• Chiastra C., MigliaVaCCa F., Martinez M.t., MalVe M. On the necessity of modelling fluid-structure interaction for stented coronary arteries . Journal of the Mechanical Behavior of Biomedical Materials . 2014;34:217-230 . • arana M., gaVira J.J., Pena e., gonzÁlez a., aBizanDa g., Cilla M. et al . Epicardial delivery of collagen patches with adipose-derived stem cells in rat and minipig models of chronic myocardial infarction . Biomaterials .
2014;35(1):143-151 .
Highlights
Institution: Universidad de Zaragoza Contact: Universidad de Zaragoza · Calle Pedro Cerbuna, 12 . 50009 Zaragoza E-mail: mdoblare@unizar .es · http://gemm .unizar .es/gemm .php?idioma=es&loc=inicio&idbio=
Researchers of our group are leading competitive research projects during 2014: • Incidencia de los fenómenos de transporte en la hidrólisis enzimática y aplicación de mecánica de fluidos
computacional en problemas de escalado (MIXING) . RTC-2014-1826-3 . Investigador responsable: Luis J . Fer- nández Ledesma • Diseño y mejora de dispositivos intravasculares recubiertos de farmaco mediante una he- rramienta computacional . Aplicación al diseño de stent y balones en lesiones estenóticas . DPI2013-44391-P . Investigador responsable: Miguel Angel Martínez Barca / Estefanía Peña Baquedano • Desarrollo de una herramienta computacional para el estudio de problemas de interacción fluido-estructura aplicada a pro- blemas cardiovasculares. DPI2010-20746-C03-01. Investigador responsable: Miguel Angel Martínez Barca • Modelado y Simulación del envejecimiento de arterias debido a Aterosclerosis . PRI-AIBDE-2011-1216 . Inves- tigador responsable: Estefanía Peña Baquedano. • MODELADO BIOMECANICO DEL TEJIDO MUSCULO-ES- QUELETICO ABDOMINAL . CICYT . DPI2011-27939-C02-01 . Investigador responsable: Begoña Calvo Calzada • POPCORN / Development of corneal biomechanical model. Dynamic topographical characterization based on 3D plenoptic imaging . FP7-SME-2013 606634 . Unión Europea . Investigador/es responsable/es en UNIZAR: María Begoña Calvo Calzada
One of the main achievements of 2014 was the award of two multidisciplinary projects CIBER called MICROAN- GIOTHECAN and Micropod . These projects, both have collaborative nature with various institutions are public call obtained in 2014 . Principal Investigator Ochoa Ignacio Garrido . Coordinator of the line of Biomedical Engineering and Nanoscience at the IIS (Institute for Health Research) of Aragon .L . J . Fernández Ledesma . 2014 .
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