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Purpose and functionality:
This platform provides both 2D and 3D materials and constructions that provide sup- port to projects primarily comprised in the Biomaterials and Advanced Therapies Pro- gramme, specifically in the lines of Prostheses and Implants and Tissue Engineering, and in the line of Nanomedicine, especially in Therapeutic Nanosystems . It provides services for:
• Functionalizing devices and biosensors by means of dispensing solutions
• Surface treatments to favour integration; coating implants and prostheses with bioactive factors
• Creating 3D matrices with materials such as polymers, ceramics and composites; preparing scaffolds or prototypes for testing; or even functionalizing by adding stem cells
• Production and characterization of pure nanometric-sized drug substances, vesicu- lar systems, nanosuspensions or compounds formed by a biocompatible polymer and a drug substance
• Synthesis of particles and functionalized surfaces
• Pilot-scale preparation and characterization of molecular materials with a controlled micro-nano- and supramolecular structure with different functionalities
• Repeatedly stamping dies of various composites to study the behaviours of cells or other elements given these situations; implant integration assays; prototyping and manufacturing micro/nano arrays of electrodes for implants
• Growth of materials on surfaces improving the bio-electronic interface in recording biomonitoring signals
• Producing micro-/nano-structures present in microelectronic devices and surface characterization
TISSUE, BIOMATERIAL AND SURFACE CHARACTERIZATION PLATFORM
Units:
• Nanostructured liquid characterization • Tissue characterization • Magnetic nanoparticle characterization, guiding and locating • Surface characterization and calorimetry • Confocal microscopy • Nanotoxicology
General Objective:
To provide characterization services for materials, biological tissues and nanosystems developed in intramural projects and within CIBER-BBN groups .
Purpose and functionality:
This platform provides characterization support for the materials obtained in the Mate-
rial Production Platform, among others . Its functions are:
• Characterization of the functional behaviour of 2D and 3D constructions as tissue scaffolds from the mechanical, structural and microstructural point of view
• Morphological and mechanical-structural characterization of biological tissues
• Characterization of the surface composition and structure of materials and biologi- cal solutions (containing bioactive factors or cells) .
• Real time in vitro and ex vivo study of cell and tissue behaviour, respectively, in res- ponse to the potential therapeutic agents identified, as well as to identify and locate the targets of said agents
• Characterization of intermolecular interactions, material functionalization quality control
• Conducting the in vitro and in vivo toxicological studies necessary for assuring that the new materials are innocuous
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