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RESEARCH GROUPS
Nanomembrane Group
Programme: Nanomedicine
Lead Researcher: Sanz Carrasco, Fausto Group Members
STAFF MEMBERS: Camarero Palao, Nuria | Giannotti, Marina Inés ASSOCIATED MEMBERS: Gorostiza Langa, Pau | Hernández Borrell, Jordi | Montero Barrientos, María
Teresa | Torrent Burgues, Joan
CONTRIBUTORS: Artés Vivancos, Juan Manuel | Bahamonde Santos, María Isabel | Bautista Barrufet, Antonio | Cortijos Aragonés, Albert | López Martínez, Montserrat | Martín Quirós, Andrés | Matencio Lloberas, Sonia | Oliva Herrera, Mireia | Palacios Padrós, Anna | Pozuelo Ruiz, Marta | Redondo Morata, Lorena
Main lines of research
Electrochemical STS of biomimetic membranes with redox systems . Measuring the energy levels of a protein under a variety of experimental conditions (in the presence of illumination or certain cofactors and partner proteins) will provide new insights into the detailed electron transfer mechanisms . Mechanical stability at the molecular level . Nanomechanics of lipid bilayers and other biosystems . Understanding the effect of mechanical stress on biological membranes is of fundamental importance since cells are known to naturally perform their function under the effect of a complex combination of forces . Development and application of light-activated nanoswitches to control the activity of protein complexes and cells . We will develop new optical switches (like the light-gated glutamate receptor LiGluR) in order to study the processes involved in neurosecretion, exocytosis and endocytosis .
Vectorization of therapeutically active molecules . We prepare and characterize therapeutic agent (drugs, peptides, proteins, genetic material...) release systems based on supramolecular conjugates which allow reaching the point of action in a directed and effective manner .
136 CIBER-BBN » Annual report 2014