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Most relevant scientific articles
• roCha B., CalaMia V., Casas V., CarrasCal M., BlanCo F.J., ruiz-roMero C. Secretome analysis of human mesenchymal stem cells undergoing chondrogenic differentiation . Journal of Proteome Research . 2014;13(2):1045-1054 .
• Burguera e.F., Vela-anero t., Magalhaes J., MeiJiDe-FailDe r., BlanCo F.J. Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes . Osteoarthritis and Cartilage . 2014;22(7):1026-1035 .
• CiCione C, Muiños-lóPez e, herMiDa-góMez t, Fuentes-Boquete i, Díaz-PraDo s, BlanCo FJ. Alternative proto- cols to induce chondrogenic differentiation: transforming growth factor-β superfamily .Cell and tissue banking . 2014 .
• Magalhaes J., CraWForD a., hatton P.V., BlanCo F.J., roMan J.s . Poly(2-ethyl-(2-pyrrolidone) methacryla- te) and hyaluronic acid-based hydrogels for the engineering of a cartilage-like tissue using bovine articular chondrocytes . Journal of Bioactive and Compatible Polymers . 2014;29(6):545-559 .
• VolkMer t., Magalhaes J., sousa V., santos l.a., Burguera e.F., BlanCo F.J. et al . 2-(dimethylamino)ethyl methacrylate/(2-hydroxyethyl) methacrylate/α-tricalcium phosphate cryogels for bone repair, prepara- tion and evaluation of the biological response of human trabecular bone-derived cells and mesenchy- mal stem cells . Polymers . 2014;6(10):2510-2525 .
Highlights
Institution: Servicio Gallego de Salud Contact: Complejo Hospitalario Universitario A Coruña . Centro de Investigación Biomédica, Servicio de Reumatología, C/ As Xubias, 84 . 15006 A Coruña · Teléfono: (+34) 981 176 399 ext . 292494 E-mail: Cristina .Ruiz .Romero@sergas .es · Website: www .inibic .es
In 2014, GBTTC-CHUAC has generated 17 peer-reviewed publications, describing: the relevance of secre- tome analysis for understanding possible mechanisms responsible for cartilage formation and the poten- tial of a panel of extracellular markers described for the evaluation of tissue development in cell therapy or cartilage tissue engineering (TE) approaches; the therapeutic potential of exogenous sources of H2S in osteoarthritis (OA) through the regulation of relevant genes involved in the pathology and progression of the OA disease; the efficacy of different growth factors for the chondrogenic differentiation of mesenchy- mal stem cells; and the potential of hybrid hydrogels (PEPM-HA) for applications in cartilage TE .
GBTTC-CHUAC has obtained financial support from Xunta de Galicia to create the first Galician Network of Biomaterials together with other 5 groups, and obtained funding from the ISCIII for the development of strategies to identify markers of cartilage degradation (PI14/01707) . The group has also started a science communication project funded by FECYT “Biomedicine with and for the Society” with the main goal of promoting public awareness of biomedical research through social media .
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