Page 112 - MEMOCiberesp014-ENG
P. 112
RESEARCH GROUPS
NanoBioCel: Micro and Nano Technologies,
Biomaterials and Cells Research Group
Programme: Nanomedicine
Lead Researcher: Pedraz Muñoz, José Luis Group Members
STAFF MEMBERS: Ciriza Astrain, Jesús | Losada Narvaez, Ángela ASSOCIATED MEMBERS: Esquisabel Alegría, Amaia | Hernández Martín, Rosa María | Igartúa Olaechea,
Manoli | Orive Arroyo, Gorka | Zarate Sesma, Jon .
CONTRIBUTORS: Agirre Díez, Mireia | Egusquiaguirre Martín, Susana Patricia | Gainza Luzea, Garazi | Garate Letona , Ane | Gartziandia López de Goikoetxea, Oihane | Herrán Martínez, Enara | Moreno Sastre, María | Pastor Navarro, Marta | Saenz del Burgo Martínez, Laura | Salvador Martínez, Aiala | Santos Vizcaíno, Edorta .
Main lines of research
• Microencapsulation of alive cells: Design and optimization of polymeric systems for immobilization of cells with therapeutic activity . This system provides protection to cells against the host’s immune response due to its technological design, and at the same time, it turns into a controlled release phar- maceutical system .
• Micro and nano-particles as vaccine administration systems of peptides and proteins: Promising results obtained by our research group support the use of these drug (antigen) carrier systems to develop vaccines, as demonstrated by the results after their administration by different routes in laboratory animals (mice and monkeys), inducing a sustained and strong immune response .
• Non viral vectors for gene therapy purposes: Design and optimization of non-viral vectors based on lipidic and polymeric nanoparticles to transfect eukaryotic cells with therapeutic genes .
• Development of modified release formulations: Development and optimization of drug delivery sys- tems based on new polymers to obtain a sustained release profile of drugs .
112
CIBER-BBN » Annual report 2014