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• B A, C J, s s, y s, W iB, m-l m .. Analysis of microa-
Most relevant eloquiAlvoernAAnilsonArtínomAset Al
rrays by MALDI-TOF MS. Angew Chem Int Ed Engl. 2013 Jul 15;52(29):7477-81.
scientific
• reiChArdt nC, mArtín-lomAs m, PenAdés s. Glyconanotechnology. Chem Soc Rev. 2013,
articles
May 21,42(10): 4358-76.

• Chiodo F, mArrAdi m, teFsen B, sniPPe h, vAn die i, PenAdés s. High sensitive detection of
carbohydrate binding proteins in an ELISA-solid phase assay based on multivalent

glyconanoparticles. PLoS One. 2013, 8(8): e73027.

• etXeBArriA J, sernA s, Beloqui A, mArtín-lomAs m, reiChArdt nC. Three-dimensional
arrays using glycoPEG tags: glycan synthesis, purification and immobilisation. Che-

mistry. 2013 Apr 8;19(15):4776-85.

• Guedes n, CzeChurA P, eCheverriA B, ruiz A, miChelenA o, mArtín-lomAs m et Al.. Toward
the solid-phase synthesis of heparan sulfate oligosaccharides: evaluation of iduronic

acid and idose building blocks. J Org Chem. 2013 Jul 19;78(14):6911-34.

In the frame of a contract with Midatech Biogune SL (CENIT-Advance Molecu-
Highlights
lar Imaging Technique, AMIT) aiming at developing contrast agents to cross the
blood brain barrier (BBB), 68Ga-based gold glyconanoparticles incorporating spe-

cific peptides have been evaluated by PET and gamma-counter techniques in

healthy rats. The results are published in the J. Am. Chem. Soc. 2014, 136,
449-457 (68Ga-Labeled Gold Glyconanoparticles for Exploring Blood-Brain Barrier

Permeability: Preparation, Biodistribution Studies, and Improved Brain Uptake via
Neuropeptide Conjugation)

12 publications in 2013, 11 indexed, 4 in the first decile and 6 in the first quartile

Two PhD Theses have been presented:

• Gold glyconanoparticles as multivalent nanocarriers for carbohydrate antigens.
Fabrizio Chiodo. Universidad del País Vasco (UPV-EHU). 11 de Marzo 2013.

• Exploring gold glyconanoparticles as multivalent carrier for specific molecules
involved in HIV-1 infection. Paolo di Gianvincenzo. Universidad del País Vasco

(UPV-EHU). 4 de Octubre 2013

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